Interaction of apolipoprotein(a) with apolipoprotein B-containing lipoproteins.
نویسندگان
چکیده
منابع مشابه
Apolipoprotein B-containing lipoproteins and atherosclerotic cardiovascular disease
Cholesterol-rich, apolipoprotein B (apoB)-containing lipoproteins are now widely accepted as the most important causal agents of atherosclerotic cardiovascular disease. Multiple unequivocal and orthogonal lines of evidence all converge on low-density lipoprotein and related particles as being the principal actors in the genesis of atherosclerosis. Here, we review the fundamental role of atherog...
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RATIONALE Plasma apolipoprotein (apo)M is mainly associated with high-density lipoprotein (HDL). HDL-bound apoM is antiatherogenic in vitro. However, plasma apoM is not associated with coronary heart disease in humans, perhaps because of a positive correlation with plasma low-density lipoprotein (LDL). OBJECTIVE We explored putative links between apoM and very-low-density (VLDL)/LDL metabolis...
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Received for publication 16 November 1981 and in revised form 18 August 1982. human fibroblasts. The binding activity of plasma from patients (per milligram of protein) was about half that of plasma from normal volunteers. All binding activity in the patients' plasma was found to reside in the HDL fraction. The binding activity of the patients' HDL (on a total protein basis) was intermediate be...
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Because lipoproteins containing apolipoprotein A (ApoA-I + ApoA-II) or apolipoprotein B (ApoB) seem to exert opposite effects as risk factors for coronary heart disease, we decided to determine the separability of these two major plasma lipoproteins by procedures originally designed to separate high-density from low- and very-low-density lipoproteins. The presumably ApoB-free lipoproteins isola...
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taining Lipoproteins in Obese Girls, Piers R. Blackett, Robin Germany, Boureima Sambo, and Petar Alaupovic, ( Department of Pediatrics, 2 University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104; 3 Medical Research Foundation, Oklahoma City, OK 73109; * address correspondence to this author at: Children’s Hospital of Oklahoma, Room 2426, 940 NE 13th St., Oklahoma City, OK 73104; f...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1991
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)67620-9